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Case reports in ophthalmological medicine 39건

  1. [해외논문]   Reconstruction of Photoreceptor Outer Layers after Steroid Therapy in Solar Retinopathy  

    Nakamura, Masaki (Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan ) , Komatsu, Koji (Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan ) , Katagiri, Satoshi (Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan ) , Hayashi, Takaaki (Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan ) , Nakano, Tadashi (Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan)
    Case reports in ophthalmological medicine v.2018 ,pp. 1 - 5 , 2018 , 2090-6722 ,

    초록

    Purpose. To report the clinical course of solar retinopathy after steroid therapy. Case Presentation. A 45-year-old male gazed at the sun and noticed bilateral central scotoma and decreased vision after the episode. After 7 weeks from onset, ophthalmic examinations were firstly performed. Decimal best corrected visual acuity (BCVA) was decreased to 0.8 and 0.7 in the right and left eyes. Funduscopy showed a tiny, yellowish spot in the fovea bilaterally. Corresponding to the lesion, optical coherence tomography (OCT) images showed an elevated and blurred ellipsoid zone and loss of the interdigitation zone. A posterior sub-Tenon triamcinolone injection in the right eye and oral prednisolone therapy were performed as a medication. BCVA was improved to 1.2 and 1.0 in the right and left eyes at 9 weeks after medication. OCT images showed ellipsoid zone was gradually improved bilaterally, which became nearly normal at 4 weeks in the right eye and at 21 weeks in the left eye. The loss of the interdigitation zone remained at 12 weeks in the right eye and at 21 weeks at the left eye. Conclusions . We described a case with solar retinopathy who exhibited anatomical recovery of the photoreceptor outer layers by steroid therapy, started after 7 weeks from onset.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

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  2. [해외논문]   Retinal and Preretinal Hemorrhages in a Patient Receiving Hyper-CVAD Chemotherapy for T-Cell Acute Lymphoblastic Leukemia  

    Peddada, Krishi (Department of Ophthalmology, Drexel University College of Medicine, Philadelphia, PA, USA ) , Weiss, Stephanie J. (Department of Ophthalmology, Drexel University College of Medicine, Philadelphia, PA, USA ) , Kumar, Shaina (Department of Ophthalmology, Drexel University College of Medicine, Philadelphia, PA, USA ) , Malik, Deepika (Department of Ophthalmology, Drexel University College of Medicine, Philadelphia, PA, USA)
    Case reports in ophthalmological medicine v.2018 ,pp. 1 - 4 , 2018 , 2090-6722 ,

    초록

    Hyperfractionated cyclophosphamide, vincristine, adriamycin, and dexamethasone (Hyper-CVAD) is an important chemotherapeutic regimen for acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma. We present a case of a 23-year-old male with T-cell ALL and visual acuity of 20/20 in the right eye and 20/25 in the left eye who developed significant changes in his vision after starting Hyper-CVAD therapy. The patient initially presented with cotton wool spots in the fundus shortly after starting the regimen. After going through the induction phase of chemotherapy, he had a sudden decline in his vision to light perception in the left eye. Posterior segment exam revealed retinal ischemia and multilayered hemorrhages in both eyes as well as a large preretinal hemorrhage obscuring the fovea in the left eye. Labs associated the appearance of these hemorrhages with a significant decrease in hemoglobin and a platelet count of 5 K/ μ L. A Nd:YAG laser applied in the left eye at the posterior hyaloid face allowed blood to drain into the vitreous cavity and brought the patient's visual acuity back to baseline. Hyper-CVAD is an aggressive chemotherapy regimen that can cause severe thrombocytopenia secondary to myelosuppression. Frequent retinal evaluations and timely intervention is advisable in these cases as extensive intraretinal hemorrhages may cause irreversible damage.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  3. [해외논문]   Intraocular Lymphoma or Infection? Subretinal Aspirate Confirms the Diagnosis  

    Saad, A. (James Cook University Hospital (JCUH), Middlesbrough, UK ) , Salceanu, S. O. (James Cook University Hospital (JCUH), Middlesbrough, UK ) , Oswal, K. (James Cook University Hospital (JCUH), Middlesbrough, UK ) , Aboushrkh, A. (Zagazig University, Zagazig, Egypt ) , Hamada, D. (Zagazig University, Zagazig, Egypt)
    Case reports in ophthalmological medicine v.2018 ,pp. 1 - 4 , 2018 , 2090-6722 ,

    초록

    Purpose. To demonstrate the importance of subretinal biopsy to reach a diagnosis when vitreous biopsy is negative or inconclusive. Methods. A 54-year-old Caucasian gentleman presented with bilateral anterior uveitis at JCUH. He initially responded to topical steroids and dilating agents. Subsequently he developed bilateral panuveitis and cataract with poor response to treatment. Detailed workup had been done to rule out infectious etiology. A suspicion of lymphoma was considered and vitreous biopsy sample was taken from one eye, which was inconclusive. Then, to help with definitive diagnosis vitreous sample, subretinal aspirate and retinal biopsy were taken. Results. Subretinal aspirate revealed Aspergillus niger . Treatment was initiated accordingly. Conclusions. Subretinal aspirate and retinal biopsy can help with diagnosis of unusual clinical panuveitis like presentation.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  4. [해외논문]   Cytomegalovirus Retinitis in Primary Immune Deficiency Disease  

    Ngai, Jia Jeane (Department of Ophthalmology, Hospital Bintulu, Sarawak, Malaysia ) , Chong, Ka Lung (Department of Ophthalmology, Hospital Bintulu, Sarawak, Malaysia ) , Oli Mohamed, Shelina (Department of Ophthalmology, Hospital Shah Alam, Selangor, Malaysia)
    Case reports in ophthalmological medicine v.2018 ,pp. 1 - 5 , 2018 , 2090-6722 ,

    초록

    Introduction . To report an unusual case of CMV retinitis in Primary Immune Deficiency Disease (PIDD). Case Report . 13-year-old child with combined T and B cell deficiencies was diagnosed of bilateral zone 1 CMV retinitis. Intravitreal injections were unable to be given in a regular and timely manner under general anaesthesia due to her underlying systemic disease. The child was treated with intravenous ganciclovir for 8 weeks until eventual resolution of the retinitis. However, visual acuity deteriorated due to progressive optic nerve involvement. Conclusion . Paediatric patients often do not notice subtle symptoms of CMV retinitis. Although ocular manifestations are uncommon in PIDD, recognition and high index of suspicion will allow for timely referral, diagnosis, and treatment to be instituted for better visual outcomes.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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    Fig. 1 이미지
  5. [해외논문]   Full Thickness Retinal Hole Formation after Nd:YAG Laser Hyaloidotomy in a Case with Valsalva Retinopathy  

    Goker, Yasin Sakir (Department of Ophthalmology, University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey ) , Tekin, Kemal (Kars State Hospital, Ophthalmology Department, Kars, Turkey ) , Ucgul Atilgan, Cemile (Department of Ophthalmology, University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey ) , Kosekahya, Pinar (Department of Ophthalmology, University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey ) , Yilmazbas, Pelin (Department of Ophthalmology, University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey)
    Case reports in ophthalmological medicine v.2018 ,pp. 1 - 4 , 2018 , 2090-6722 ,

    초록

    A 27-year-old male was presented with a sudden onset of visual loss in his right eye. A secondary care center referred the patient with fundus photographs which were screened 4 days before and after the Nd: YAG laser hyaloidotomy treatment. Snellen acuity was 10/10 in both eyes. Fundus examinations revealed a retinal pigment epithelium (RPE) alteration at the margin of the inferior temporal arterial vascular arcade in the right eye and resolved preretinal and subretinal hemorrhages were seen in the macula. A diagnosis of Valsalva retinopathy was made based on the history and the treatment photographs of Nd:YAG laser hyaloidotomy. At 1st month examination all hemorrhages were resolved but RPE alterations were still at the margin of the inferior temporal arterial vascular arcade. The optical coherence tomography angiography (OCTA) images revealed 2 lesions. On en face OCT angiogram of OCTA full thickness retinal hole formation and ellipsoid zone damage at the superior and inferior margin of the inferior temporal arterial vascular arcade were seen. Superficial vascular plexus was also damaged at that region. The projection of the evacuation of blood from subhyaloid space and the full thickness retinal hole formation were the same, indicating that the partial and full thickness retinal holes were created by the laser treatment.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  6. [해외논문]   Bilateral Iris Mammillations in Amblyopic Eyes without Oculodermal Melanocytosis or Neurofibromatosis  

    Yamamoto, Megumi (Department of Ophthalmology, Teikyo University School of Medicine, Tokyo 173-8605, Japan ) , Mimura, Tatsuya (Department of Ophthalmology, Teikyo University School of Medicine, Tokyo 173-8605, Japan ) , Matsumoto, Koichi (Department of Ophthalmology, Teikyo University School of Medicine, Tokyo 173-8605, Japan ) , Hamano, Shigeki (Department of Ophthalmology, Teikyo University School of Medicine, Tokyo 173-8605, Japan ) , Nanba, Hisataka (Department of Ophthalmology, Teikyo University School of Medicine, Tokyo 173-8605, Japan ) , Ubukata, Shoko (Department of Ophthalmology, Teikyo University School of Medicine, Tokyo 173-8605, Japan ) , Watanabe, Emiko (Department of Ophthalmology, Teikyo University School of Medicine, Tokyo 173-8605, Japan ) , Mizota, Atsushi (Department of Ophthalmology, Teikyo University School of Medicine, Tokyo 173-8605, Japan)
    Case reports in ophthalmological medicine v.2018 ,pp. 1 - 5 , 2018 , 2090-6722 ,

    초록

    Purpose . Iris mammillations are related to oculodermal melanosis and iris nevi. We report a rare case of bilateral simple iris mammillations without ocular melanosis or systemic neuronal disorders. Case Report . A healthy 10-year-old Japanese girl was found incidentally to have bilateral iris mammillations while being treated for amblyopia. The best-corrected visual acuity was 20/40 in both eyes. Ocular examination showed evenly spaced, uniform-size, iris protrusions completely covering the iris surface bilaterally. There were no other ocular or neurological abnormalities. Conclusion . To the best of our knowledge, this is the first report of bilateral iris mammillations in Japan. Our case emphasizes that iris mammillations can occur even without ocular melanocytosis or systemic diseases.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  7. [해외논문]   Topical Treatment with Cord Blood Serum in Glaucoma Patients: A Preliminary Report  

    Campos, Emilio (Ophthalmology Unit, DIMES, Alma Mater Studiorum, University of Bologna, Bologna, Italy ) , Versura, Piera (Ophthalmology Unit, DIMES, Alma Mater Studiorum, University of Bologna, Bologna, Italy ) , Giannaccare, Giuseppe (Ophthalmology Unit, DIMES, Alma Mater Studiorum, University of Bologna, Bologna, Italy ) , Terzi, Adriana (Emilia Romagna Cord Blood Bank-Transfusion Service, S.Orsola-Malpighi Teaching Hospital, Bologna, Italy ) , Bisti, Silvia (Vision Lab, DISCAB, University of L'Aquila, L'Aquila, Italy ) , Di Marco, Stefano (Vision Lab, DISCAB, University of L'Aquila, L'Aquila, Italy ) , Buzzi, Marina (Emilia Romagna Cord Blood Bank-Transfusion Service, S.Orsola-Malpighi Teaching Hospital, Bologna, Italy)
    Case reports in ophthalmological medicine v.2018 ,pp. 1 - 6 , 2018 , 2090-6722 ,

    초록

    Purpose . To report data which happened to be observed in two glaucoma patients treated with Cord Blood Serum (CBS) eye drops. Design . A case report and retrospective data analysis. Methods . CBS topical eye drops, characterized in advance for growth factors (GFs) content, were administered for two months with the aim to relieve their subjective symptoms, in two patients who had referred ocular surface discomfort, although in absence of any sign of keratopathy. As patients were also affected by advanced glaucoma at risk of vision loss and under treatment with hypotensive drugs, they had been also monitored over the same period with IOP controls and visual field tests in our unit. Results . During subsequent visits, data from Mean Deviation and Pattern Standard Deviation in the visual fields were retrospectively collected and compared with before and after treatment with CBS, and an amelioration was observed. Conclusions . CBS contains a combination of GFs, which potentially exert a neuroprotective action and elect CBS as an interesting natural source to be delivered in neurodegenerative ocular disorders. The incidentally observed amelioration in these two patients deserves further investigation in this respect.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  8. [해외논문]   Single-Stage Orbital Socket Reconstruction Using the Oversized Dermis Fat Graft and the 22 mm Silicone Orbital Implant after an Extended Enucleation  

    Kuzmanović (University Eye Clinic, Faculty of Dental Medicine and Health Care Osijek, Faculty of Medicine Osijek, University Josip Juraj Strossmayer in Osijek, University Hospital “Sveti Duh”, Zagreb, Croatia ) , Elabjer, Biljana (University Eye Clinic, Faculty of Dental Medicine and Health Care Osijek, Faculty of Medicine Osijek, University Josip Juraj Strossmayer in Osijek, University Hospital “Sveti Duh”, Zagreb, Croatia ) , Buš (University Eye Clinic, Faculty of Dental Medicine and Health Care Osijek, Faculty of Medicine Osijek, University Josip Juraj Strossmayer in Osijek, University Hospital “Sveti Duh”, Zagreb, Croatia ) , ić (University Eye Clinic, Faculty of Dental Medicine and Health Care Osijek, Faculty of Medicine Osijek, University Josip Juraj Strossmayer in Osijek, University Hospital “Sveti Duh”, Zagreb, Croatia ) , , Mladen (University Eye Clinic, Faculty of Dental Medicine and Health Care Osijek, Faculty of Medicine Osijek, University Josip Juraj Strossmayer in Osijek, University Hospital “Sveti Duh”, Zag) , Miletić , , Daliborka , Bjeloš , , Mirjana , Š , arić , , Borna , Bosnar, Damir
    Case reports in ophthalmological medicine v.2018 ,pp. 1 - 4 , 2018 , 2090-6722 ,

    초록

    We would like to present a surgical technique of orbital socket reconstruction using oversized dermis fat graft and 22 mm silicone orbital implant in a single-stage after extended enucleation in two patients with massive local recurrence of anteriorly located choroidal melanoma previously treated with endoresection. Orbital tissues en bloc were removed leaving conjunctival lining only at the fornices. Simultaneously, the 22 mm silicone sphere was implanted deeply into the orbit and covered with the oversized dermis fat graft of 30 mm in height and 35 mm in length with 20 mm of the fat thickness. The graft was sutured to the residual forniceal conjunctiva with interrupted 6/0 absorbable sutures overlapping conjunctiva with the graft edge for 2 mm to facilitate the epithelization. Epithelization was completed in two months, leaving well-formed fornices with good fitting of the prosthesis. The key point of orbital socket reconstruction after extended enucleation is to restore conjunctival lining prior to volume. Thus, whenever facing a massive volume and conjunctival lining loss, simultaneous insertion of the 22 mm silicone sphere deep into the orbit combined with oversized dermis fat graft is, in our opinion, the method of choice. It proved to be safe and effective with favourable long-term results.

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    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  9. [해외논문]   Management of Congenital Clinical Anophthalmos with Orbital Cyst: A Kinshasa Case Report  

    Stahnke, Thomas (Department of Ophthalmology, Rostock University Medical Center, Doberaner Straße 140, 18057 Rostock, Germany ) , Erbersdobler, Andreas (Institute of Pathology, Rostock University Medical Center, Strempelstr. 14, 18055 Rostock, Germany ) , Knappe, Steffi (Department of Ophthalmology, Rostock University Medical Center, Doberaner Straße 140, 18057 Rostock, Germany ) , Guthoff, Rudolf F. (Department of Ophthalmology, Rostock University Medical Center, Doberaner Straße 140, 18057 Rostock, Germany ) , Kilangalanga, Ngoy J. (Eye Department, Hospital Saint Joseph, 322 Limete/Kinshasa, Democratic Republic of the Congo)
    Case reports in ophthalmological medicine v.2018 ,pp. 1 - 6 , 2018 , 2090-6722 ,

    초록

    An early developmental lack of the optic vesicle can result in congenital anophthalmia, defined as a complete absence of the eye, which can be distinguished from congenital microphthalmos, where ocular rudiments are present. Here, a rare pediatric case of congenital clinical anophthalmos with orbital cyst in the left orbit is reported. The patient was a 14-month-old girl with no other congenital defects who underwent surgical and prothetic management in St. Joseph's Hospital Kinshasa, Democratic Republic of the Congo (DRC). Surgery was carried out under general anesthesia. The cyst was punctured and its wall fully excised. Near the orbital apex pigmented elements representing iris, ciliary body, and choroidal or retinal remnants were found. The specimens were fixed in formalin for histological examination. Surgical cyst removal including socket deepening for an artificial eye was performed. Postoperative wound healing was uneventful and a satisfactory cosmetic outcome was achieved in all follow-up examinations. Histological examination revealed rudimentary ocular structures similar to degenerated lens tissue with a typical, PAS-positive capsule. Additionally, pigmented epithelial structures, which seem to be of ciliary body, iris, and choroidal or retinal-type epithelium origin, could be detected, prompting the final diagnosis, microphthalmia with dominant cyst formation.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  10. [해외논문]   Acute Onset of Exogenous Endophthalmitis after Dexamethasone Implant Injection Treated without Implant Removal  

    Bastakis, George G. (Ophthalmology Clinic, Medical Retina & Vitreoretinal Surgery Department, Venizeleio Hospital of Crete, Knossos Avenue 44, Heraklion of Crete, Greece ) , Stavrakakis, Anastasios (Ophthalmology Clinic, Medical Retina & Vitreoretinal Surgery Department, Venizeleio Hospital of Crete, Knossos Avenue 44, Heraklion of Crete, Greece ) , Nikolaos, Avgoustinakis (Ophthalmology Clinic, Medical Retina & Vitreoretinal Surgery Department, Venizeleio Hospital of Crete, Knossos Avenue 44, Heraklion of Crete, Greece ) , Dimopoulos, Dimitris (Ophthalmology Clinic, Medical Retina & Vitreoretinal Surgery Department, Venizeleio Hospital of Crete, Knossos Avenue 44, Heraklion of Crete, Greece ) , Pappas, George (Ophthalmology Clinic, Medical Retina & Vitreoretinal Surgery Department, Venizeleio Hospital of Crete, Knossos Avenue 44, Heraklion of Crete, Greece)
    Case reports in ophthalmological medicine v.2018 ,pp. 1 - 3 , 2018 , 2090-6722 ,

    초록

    We present a case of acute endophthalmitis after intravitreal dexamethasone implant injection and discuss the management of this rare and challenging case in which the implant could not be removed. A 50-year-old woman with a history of branch retinal vein occlusion in the right eye was treated with intravitreal dexamethasone implant injection for macular oedema. Four days after injection, the patient was admitted to the department with acute pain, decreased vision, and redness. A diagnosis of acute post-intravitreal injection endophthalmitis was made. A 23-guage (23G) vitrectomy was performed immediately to remove the implant, and a vitreous tap for culture and polymerase chain reaction was acquired during the procedure. We were unable to remove the dexamethasone implant during the vitrectomy because of dense membrane formation. At the end of the procedure, we injected intravitreal antibiotics (vancomycin and amikacin), and the patient was treated with fortified topical antibiotics and steroids. At the time of writing, 5 years later, the patient retains a best corrected visual acuity of 10/10 (6/6) with dexamethasone implant therapy maintenance. Intravitreal dexamethasone implant-associated endophthalmitis is a rare and challenging condition. Immediate 23G pars plana vitrectomy, even without removal of the implant, can lead to favourable visual results.

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