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Evidence-based Complementary and Alternative Medic... 760건

  1. [해외논문]   Essential Oil of Artemisia annua L.: An Extraordinary Component with Numerous Antimicrobial Properties  

    Bilia, Anna Rita (Department of Chemistry, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy ) , Santomauro, Francesca (Department of Health Sciences, University of Florence, Viale G.B. Morgagni 48, 50134 Florence, Italy ) , Sacco, Cristiana (Department of Health Sciences, University of Florence, Viale G.B. Morgagni 48, 50134 Florence, Italy ) , Bergonzi, Maria Camilla (Department of Chemistry, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy ) , Donato, Rosa (Department of Health Sciences, University of Florence, Viale G.B. Morgagni 48, 50134 Florence, Italy)
    Evidence-based Complementary and Alternative Medicine : eCAM v.2014 ,pp. 159819 , 2014 , 1741-427x ,

    초록

    Artemisia annua L. (Asteraceae) is native to China, now naturalised in many other countries, well known as the source of the unique sesquiterpene endoperoxide lactone artemisinin, and used in the treatment of the chloroquine-resistant and cerebral malaria. The essential oil is rich in mono- and sesquiterpenes and represents a by-product with medicinal properties. Besides significant variations in its percentage and composition have been reported (major constituents can be camphor (up to 48%), germacrene D (up to 18.9%), artemisia ketone (up to 68%), and 1,8 cineole (up to 51.5%)), the oil has been subjected to numerous studies supporting exciting antibacterial and antifungal activities. Both gram-positive bacteria ( Enterococcus , Streptococcus , Staphylococcus , Bacillus , and Listeria spp.), and gram-negative bacteria ( Escherichia , Shigella , Salmonella , Haemophilus , Klebsiella , and Pseudomonas spp.) and other microorganisms ( Candida , Saccharomyces , and Aspergillus spp.) have been investigated. However, the experimental studies performed to date used different methods and diverse microorganisms; as a consequence, a comparative analysis on a quantitative basis is very difficult. The aim of this review is to sum up data on antimicrobial activity of A. annua essential oil and its major components to facilitate future approach of microbiological studies in this field.

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  2. [해외논문]   Dynamics of Panax ginseng Rhizospheric Soil Microbial Community and Their Metabolic Function  

    Li, Yong (Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 151 Malianwa North Road, Beijing 100193, China ) , Ying, YiXin (Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 151 Malianwa North Road, Beijing 100193, China ) , Ding, WanLong (Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 151 Malianwa North Road, Beijing 100193, China)
    Evidence-based Complementary and Alternative Medicine : eCAM v.2014 ,pp. 160373 , 2014 , 1741-427x ,

    초록

    The bacterial communities of 1- to 6-year ginseng rhizosphere soils were characterized by culture-independent approaches, random amplified polymorphic DNA (RAPD), and amplified ribosomal DNA restriction analysis (ARDRA). Culture-dependent method (Biolog) was used to investigate the metabolic function variance of microbe living in rhizosphere soil. Results showed that significant genetic and metabolic function variance were detected among soils, and, with the increasing of cultivating years, genetic diversity of bacterial communities in ginseng rhizosphere soil tended to be decreased. Also we found that Verrucomicrobia , Acidobacteria , and Proteobacteria were the dominants in rhizosphere soils, but, with the increasing of cultivating years, plant disease prevention or plant growth promoting bacteria, such as Pseudomonas , Burkholderia , and Bacillus , tended to be rare.

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  3. [해외논문]   Chinese Herbal Medicine on Dyslipidemia: Progress and Perspective  

    Guo, Ming (Cardiovascular Diseases Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China ) , Liu, Yue (Cardiovascular Diseases Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China ) , Gao, Zhu-Ye (Cardiovascular Diseases Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China ) , Shi, Da-zhuo (Cardiovascular Diseases Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China)
    Evidence-based Complementary and Alternative Medicine : eCAM v.2014 ,pp. 163036 , 2014 , 1741-427x ,

    초록

    Dyslipidemia is an independent risk factor of cardiovascular diseases. The statins are a milestone in the primary and second prevention of cardiovascular diseases and significantly improved its prognosis. Along with the long-term treatment with statins in combination with other hypolipidemic drugs or alone, its safety has attracted a particular attention in clinic, such as the elevation of transaminase and rhabdomyolysis, which have raised an idea of developing the other types of lipid-lowering agents from botanic materials. Traditional Chinese medicine (TCM) has been used in clinical practice for more than 2000 years in China and showed some beneficial effects for human health and many diseases. Recently, many studies demonstrated a favorable effect of TCM for treating dyslipidemia; however, its mechanism remains unclear or totally unknown. The progress and perspective of studies on dyslipidemia with single Chinese herb and its monomers or effective extracts during the past 10 years are discussed in the present review.

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  4. [해외논문]   Miniscalpel-Needle versus Steroid Injection for Plantar Fasciitis: A Randomized Controlled Trial with a 12-Month Follow-Up  

    Li, Shuming (Department of Rehabilitation Medicine, The First Affiliated Hospital of Guangzhou Medical University, No. 151, Yanjiang West Road, Guangzhou, Guangdong 510120, China ) , Shen, Tong (Department of Rehabilitation Medicine, The First Affiliated Hospital of Guangzhou Medical University, No. 151, Yanjiang West Road, Guangzhou, Guangdong 510120, China ) , Liang, Yongshan (Department of Rehabilitation Medicine, The First Affiliated Hospital of Guangzhou Medical University, No. 151, Yanjiang West Road, Guangzhou, Guangdong 510120, China ) , Zhang, Ying (Department of Rehabilitation Medicine, The First Affiliated Hospital of Guangzhou Medical University, No. 151, Yanjiang West Road, Guangzhou, Guangdong 510120, China ) , Bai, Bo (Department of Orthopaedics Medicine, The First Affiliated Hospital of Guangzhou Medical University, No. 151, Yanjiang West Road, Guangzhou, Guangdong 510120, China)
    Evidence-based Complementary and Alternative Medicine : eCAM v.2014 ,pp. 164714 , 2014 , 1741-427x ,

    초록

    Plantar fasciitis is the most common cause of heel pain in adults. A novel alternative medical instrument, the miniscalpel-needle (MSN), which is based on an acupuncture needle, has been recently developed in China. The objective of this study was to evaluate the effectiveness of the MSN release treatment versus that of traditional steroid injection for plantar fasciitis. Patients with plantar fasciitis were randomly assigned to 2 groups and followed up for 12 months, with 29 receiving MSN treatment and 25 receiving steroid injection treatment. The results showed that visual analog scale scores for morning pain, active pain, and overall heel pain all were decreased significantly in the MSN group from 1 to 12 months after treatment. In contrast, treatment with steroid injection showed a significant effect only at the 1-month follow-up but not at 6 or 12 months after treatment. Moreover, the MSN group achieved more rapid and sustained improvements than the steroid group throughout the duration of this study. No severe side effects were observed with MSN treatment. Our data suggest that the MSN release treatment is safe and has a significant benefit for plantar fasciitis compared to steroid injection.

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  5. [해외논문]   Pharmacokinetic Comparative Study of Gastrodin and Rhynchophylline after Oral Administration of Different Prescriptions of Yizhi Tablets in Rats by an HPLC-ESI/MS Method  

    Ge, Zhaohui (School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China ) , Xie, Yuanyuan (Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China ) , Liang, Qionglin (Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China ) , Wang, Yiming (Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China ) , Luo, Guoan (School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China)
    Evidence-based Complementary and Alternative Medicine : eCAM v.2014 ,pp. 167253 , 2014 , 1741-427x ,

    초록

    Pharmacokinetic characters of rhynchophylline (RIN), gastrodin (GAS), and gastrodigenin ( p -hydroxybenzyl alcohol, HBA) were investigated after oral administration of different prescriptions of Yizhi : Yizhi tablets or effective parts of tianma (total saponins from Gastrodiae, EPT) and gouteng (rhynchophylla alkaloids, EPG). At different predetermined time points after administration, the concentrations of GAS, HBA, and RIN in rat plasma were determined by an HPLC-ESI/MS method, and the main pharmacokinetic parameters were investigated. The results showed that the pharmacokinetic parameters C max and AUC 0– ∞ ( P Yizhi . The data indicated that the pharmacokinetic processes of GAS, HBA, and RIN in rats would interact with each other or be affected by other components in Yizhi . The rationality of the compatibility of Uncaria and Gastrodia elata as a classic “herb pair” has been verified from the pharmacokinetic viewpoint.

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  6. [해외논문]   Ginseng and Anticancer Drug Combination to Improve Cancer Chemotherapy: A Critical Review  

    Chen, Shihong (Department of Pharmacy, Xiamen Medical College, Xiamen, Fujian 361008, China ) , Wang, Zhijun (Center for Advancement of Drug Research and Evaluation, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA ) , Huang, Ying (Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA ) , O'Barr, Stephen A. (Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA ) , Wong, Rebecca A. (Center for Advancement of Drug Research and Evaluation, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA ) , Yeung, Steven (Center for Advancement of Drug Research and Evaluation, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA ) , Chow, Moses Sing Sum (Center for Advancement of Drug Research and Evaluation, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA)
    Evidence-based Complementary and Alternative Medicine : eCAM v.2014 ,pp. 168940 , 2014 , 1741-427x ,

    초록

    Ginseng, a well-known herb, is often used in combination with anticancer drugs to enhance chemotherapy. Its wide usage as well as many documentations are often cited to support its clinical benefit of such combination therapy. However the literature based on objective evidence to make such recommendation is still lacking. The present review critically evaluated relevant studies reported in English and Chinese literature on such combination. Based on our review, we found good evidence from in vitro and in vivo animal studies showing enhanced antitumor effect when ginseng is used in combination with some anticancer drugs. However, there is insufficient clinical evidence of such benefit as very few clinical studies are available. Future research should focus on clinically relevant studies of such combination to validate the utility of ginseng in cancer.

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  7. [해외논문]   Honey: A Potential Therapeutic Agent for Managing Diabetic Wounds  

    Alam, Fahmida (Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia ) , Islam, Md. Asiful (Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia ) , Gan, Siew Hua (Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia ) , Khalil, Md. Ibrahim (Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh)
    Evidence-based Complementary and Alternative Medicine : eCAM v.2014 ,pp. 169130 , 2014 , 1741-427x ,

    초록

    Diabetic wounds are unlike typical wounds in that they are slower to heal, making treatment with conventional topical medications an uphill process. Among several different alternative therapies, honey is an effective choice because it provides comparatively rapid wound healing. Although honey has been used as an alternative medicine for wound healing since ancient times, the application of honey to diabetic wounds has only recently been revived. Because honey has some unique natural features as a wound healer, it works even more effectively on diabetic wounds than on normal wounds. In addition, honey is known as an “all in one” remedy for diabetic wound healing because it can combat many microorganisms that are involved in the wound process and because it possesses antioxidant activity and controls inflammation. In this review, the potential role of honey's antibacterial activity on diabetic wound-related microorganisms and honey's clinical effectiveness in treating diabetic wounds based on the most recent studies is described. Additionally, ways in which honey can be used as a safer, faster, and effective healing agent for diabetic wounds in comparison with other synthetic medications in terms of microbial resistance and treatment costs are also described to support its traditional claims.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

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  8. [해외논문]   Traditional Medicine for Treatment of Neurodegenerative Diseases  

    Wu, Chun Fu (Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, China ) , Zhou, Wenxia (Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China ) , Suthisisang, Chuthamanee (School of Pharmaceutical Science, Mahidol University, Nakhon Pathom 73170, Thailand ) , Yang, Jing Yu (Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, China)
    Evidence-based Complementary and Alternative Medicine : eCAM v.2014 ,pp. 169821 , 2014 , 1741-427x ,

    초록

    Diabetic wounds are unlike typical wounds in that they are slower to heal, making treatment with conventional topical medications an uphill process. Among several different alternative therapies, honey is an effective choice because it provides comparatively rapid wound healing. Although honey has been used as an alternative medicine for wound healing since ancient times, the application of honey to diabetic wounds has only recently been revived. Because honey has some unique natural features as a wound healer, it works even more effectively on diabetic wounds than on normal wounds. In addition, honey is known as an “all in one” remedy for diabetic wound healing because it can combat many microorganisms that are involved in the wound process and because it possesses antioxidant activity and controls inflammation. In this review, the potential role of honey's antibacterial activity on diabetic wound-related microorganisms and honey's clinical effectiveness in treating diabetic wounds based on the most recent studies is described. Additionally, ways in which honey can be used as a safer, faster, and effective healing agent for diabetic wounds in comparison with other synthetic medications in terms of microbial resistance and treatment costs are also described to support its traditional claims.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

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  9. [해외논문]   Complementary and Alternative Medicine for Cancer Pain: An Overview of Systematic Reviews  

    Bao, Yanju (Department of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beixiange 5, Xicheng District, Beijing 100053, China ) , Kong, Xiangying (Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Nanxiaojie, Dongzhimennei Avenue, Beijing 100700, China ) , Yang, Liping (Department of Nephrology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beixiange 5, Xicheng District, Beijing 100053, China ) , Liu, Rui (Department of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beixiange 5, Xicheng District, Beijing 100053, China ) , Shi, Zhan (Department of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beixiange 5, Xicheng District, Beijing 100053, China ) , Li, Weidong (Department of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beixiange 5, Xicheng District, Beijing 100053, China ) , Hua, Baojin (Department of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beixiange 5, Xicheng District, Beijing 100053, Chin) , Hou, Wei
    Evidence-based Complementary and Alternative Medicine : eCAM v.2014 ,pp. 170396 , 2014 , 1741-427x ,

    초록

    Background and Objective . Now with more and more published systematic reviews of Complementary and Alternative Medicine (CAM) on adult cancer pain, it is necessary to use the methods of overview of systematic review to summarize available evidence, appraise the evidence level, and give suggestions to future research and practice. Methods . A comprehensive search (the Cochrane Library, PubMed, Embase, and ISI Web of Knowledge) was conducted to identify all systematic reviews or meta-analyses of CAM on adult cancer pain. And the evidence levels were evaluated using GRADE approach. Results . 27 systematic reviews were included. Based on available evidence, we could find that psychoeducational interventions, music interventions, acupuncture plus drug therapy, Chinese herbal medicine plus cancer therapy, compound kushen injection, reflexology, lycopene, TENS, qigong, cupping, cannabis, Reiki, homeopathy (Traumeel), and creative arts therapies might have beneficial effects on adult cancer pain. No benefits were found for acupuncture (versus drug therapy or shame acupuncture), and the results were inconsistent for massage therapy, transcutaneous electric nerve stimulation (TENS), and Viscum album L plus cancer treatment. However, the evidence levels for these interventions were low or moderate due to high risk of bias and/or small sample size of primary studies. Conclusion . CAM may be beneficial for alleviating cancer pain, but the evidence levels were found to be low or moderate. Future large and rigor randomized controlled studies are needed to confirm the benefits of CAM on adult cancer pain.

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    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  10. [해외논문]   Investigation of the Chemical Changes from Crude and Processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma Herbal Pair Extracts by Using Q Exactive High-Performance Benchtop Quadrupole-Orbitrap LC-MS/MS  

    Cao, Gang (College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China ) , Li, Qinglin (Zhejiang Cancer Hospital, Hangzhou 310022, China ) , Cai, Hao (College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China ) , Tu, Sicong (Faculty of Medicine, University of New South Wales, Sydney, NSW 2031, Australia ) , Cai, Baochang (College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China)
    Evidence-based Complementary and Alternative Medicine : eCAM v.2014 ,pp. 170959 , 2014 , 1741-427x ,

    초록

    The Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma herbal pair is mainly used for regulating the functions of liver and spleen, benefiting qi , and nourishing blood. However, the bioactive compounds for the pharmacological activities of the crude and processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma herbal pair extracts are still unclear to date. In the present study, Q Exactive high-performance benchtop quadrupole-Orbitrap LC-MS/MS was applied to identify the complicated components from crude and processed Paeoniae Radix Alba, crude and processed Atractylodis Macrocephalae Rhizoma, and their crude and processed herbal pair extracts. 123 and 101 compounds were identified in crude and processed Paeoniae Radix Alba samples, respectively. Meanwhile, 32 and 26 compounds were identified in crude and processed Atractylodis Macrocephalae Rhizoma samples, respectively. In the crude and processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma herbal pair extracts, co-decoction could significantly change the chemical composition of Paeoniae Radix Alba and Atractylodis Macrocephalae Rhizoma in solution. The developed method may provide a scientific foundation for deeply elucidating the processing and compatibility mechanism of Paeoniae Radix Alba and Atractylodis Macrocephalae Rhizoma.

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